Corticosteroid therapy for prevention of respiratory distress syndrome in severe preeclampsia

Article Abstract:

Corticosteroids appear to be beneficial in preventing respiratory distress in fetuses of women with preeclampsia. Preeclampsia is a complication of pregnancy characterized by high blood pressure, swelling, and mild kidney disease. Researchers randomly assigned 218 pregnant women with preeclampsia to receive intramuscular injections of betamethasone or a placebo once a week. Betamethasone reduced the rate of respiratory distress by 50% and also lowered the risk of other complications such as intraventricular hemorrhage, patent ductus arteriosus, and perinatal infection. The neonatal mortality rate was also half the rate in the placebo group.

Complications and side effects, Preeclampsia, Betamethasone

---

Collaborative trial of prenatal thyrotropin-releasing hormone and corticosteroids for prevention of respiratory distress syndrome

Article Abstract:

Thyrotropin-releasing hormone does not appear to be beneficial when combined with corticosteroids in the treatment of premature infants. These infants are more likely to develop respiratory distress syndrome and thyrotropin-releasing hormone might prevent this by helping the lungs mature. Researchers randomly assigned 370 pregnant women at risk of premature delivery to receive corticosteroids plus thyrotropin-releasing hormone or placebo. After delivery, there were no differences in infant outcome between the two groups.

Corticosteroids, Adrenocortical hormones, Thyrotropin releasing factor, Thyrotropin releasing hormone

---

Similar abstracts:

• Abstracts: A multicommunity trial for primary prevention of adolescent drug abuse: effects on drug use prevalence. Long-term follow-up results of a randomized drug abuse prevention trial in a white middle-class population
• Abstracts: Evolving strategies for management of the nongonococcal urethritis syndrome. Diphtheria in Russia a reminder of risk
• Abstracts: Antenatal corticosteroid treatment and neonatal outcomes for infants 501 to 1500 gm in the Vermont-Oxford Trials Network
• Abstracts: Minimum interval from fetal betamethasone treatment to postnatal lung responses in preterm lambs. Meta-analysis of randomized controlled trials of antenatal corticosteroid for the prevention of respiratory distress syndrome: discussion

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.