Decoy receptor springs to life and eases fibrosis
Article Abstract:
The cytokines IL-13 is induced in the transforming growth factor (TGF-beta) to study the promotion of the formation of the fibrosis tissue by such cytokines secreted during tissue damage and inflammation. The analysis revealed that IL-13 in human gut inflammation and fibrosis is very important to examine the potential of this new therapeutic target.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
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Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer
Article Abstract:
The first genetic models of peritoneal endometriosis and endometrioid ovarian adenocarcinoma in mice, both based on the activation of an oncogenic K-ras allele are presented. The ovarian cancer model described in this study summarizes the specific tumor histomorphology and metastatic potential of the human disease.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
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