Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya

Article Abstract:

This article describes the developmental strategy of an effective HIV vaccine for use in Kenya geared to elicit cell-mediated immune responses. The vaccine has two components, a DNA vector and a modified vaccinia virus Ankara, which together express a common 'chimeric' protein of the HIV genome.

Health aspects, Planning, Usage, Testing, Clinical trials, Design and construction, Kenya, DNA vaccines, Viral vaccines, HIV antigens

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HIV vaccines 1983-2003

Article Abstract:

ANNOTATION: "HIV SPECIAL" The result after Twenty years of research to find a for treatment of AIDS is illustrated. There are three challenge corresponding to find a vaccine that can stimulate monoclonal neutralizing bodies, optimize T-cells inducing vaccines and to increase the capacity to carry out phase 3 trials in developing countries.

United States, Analysis, Vaccines, AIDS treatment

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Is an HIV vaccine possible?

Article Abstract:

Whether an HIV vaccine is or is not a possibility is discussed, with the conclusion that promising findings have been seen in recent studies. Novel vaccines that bring on cellular immunity have been found to able to protect macaques from infection with simian immunodeficiency virus. The search for an HIV vaccine is going toward the CD8(super.+) cytotoxic T-lymphocyte (CTL) response.

Physiological aspects, T cells, Macaques, Simian immunodeficiency virus

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