Effect of antenatal exposure to Saint John's wort (Hypericum) on neurobehavior of developing mice

Article Abstract:

The herbal medicine St. John's wort had no adverse neurological or behavioral effects on the offspring of mice who received the herb in their food in doses comparable to those a human would take adjusted for body weight. St. John's wort has been shown to be effective for treating depression and has fewer side effects than antidepressant drugs.

Evaluation

---

Effect of prenatally administered hypericum (St John's wort) on growth and physical maturation of mouse offspring

Article Abstract:

A study in mice shows that St. John's wort should have no serious adverse effects on the fetus when taken by pregnant women. This herb has been shown to be effective in treating depression and has fewer side effects than many antidepressants.

---

Impact of multiple antenatal doses of betamethasone on growth and development of mice offspring

Article Abstract:

Multiple doses of betamethasone in pregnant mice, including toxic dosages, did not effect the long-term growth, functional development, or reproductive capabilities of the surviving young. Sixty pregnant mice received two, four, or eight doses of betamethasone or placebo. Treated mice had fewer live births and fetal growth restriction, most pronounced at toxic, eight-dose levels. No effects persisted after 7 days. No long-term differences in growth, functional development, or fertility were seen between the offspring of treated or untreated mice.

Growth (Physiology), Betamethasone

Similar abstracts:

• Abstracts: Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis
• Abstracts: Effect of reperfusion on biventricular function and survival after right ventricular infarction. Multiple complex coronary plaques in patients with acute myocardial infarction
• Abstracts: Injection-related risk behaviors in young urban and suburban injection drug users in Chicago (1997-1999). Prevention of HIV infection in street-recruited injection drug users
• Abstracts: Effect of previous vaginal delivery on the risk of uterine rupture during a subsequent trial of labor. Rate of uterine rupture during a trial of labor in women with one or two prior cesarean deliveries

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.