Effect of supplementation of smoking men with plain or slow release ascorbic acid on lipoprotein oxidation
Article Abstract:
Men who smoke 11-40 cigarettes daily were enrolled in a randomized, single blinded and placebo-controlled clinical trial to determine the effect of a two-month daily oral administration of 500 mg ascorbic acid supplement on lipoprotein oxidation among regular smokers. Ascorbic acid did not show any antioxidant activity in in vitro lipid peroxidation resistance or on total antioxidative capacity of low density lipoproteins. Vitamin C even appears to promote malondialdehyde production probably via metal ion-ascorbic acid-mediated oxidation and increase in catalytic ferrous iron in the body.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1997
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Unpredictable intra-individual variations in serum homocysteine levels on folic acid supplementation
Article Abstract:
Homocysteine levels were measured on samples collected from subjects given an eight-day daily supplementation of 1 mg folic acid. This was done to determine the usefulness of the changes in homocysteine values induced by folic acid supplementation as an indicator of asymptomatic folate deficiency. The results revealed inconsistent changes in homocysteine levels seen as intraindividual variations, indicating that such parameter cannot be used to identify individuals with folate deficiency.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1997
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Low serum folate concentrations are associated with an excess incidence of acute coronary events: The Kuopion Ischaemic Heart Disease Risk Factory Study
Article Abstract:
The hypothesis that low serum folate concentrations are linked to increased risk of acute coronary events in men without prior coronary heart disease (CHD) was tested middle aged-men from eastern Finland. Moderate-to-high rates of serum folate were found to be linked to reduced incidence of acute coronary events.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 2000
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