Effects of Controlled-Release Metoprolol on Total Mortality, Hospitalizations, and Well-being in Patients With Heart Failure
Article Abstract:
The beta blocker metoprolol not only reduces the mortality rate in patients with congestive heart failure, it improves their symptoms and decreases the amount of time spent in the hospital. This was the conclusion of researchers who randomly assigned 3,991 patients in 14 countries with congestive heart failure to take extended release metoprolol or a placebo. The mortality rate was 31% lower in the patients taking metoprolol and they spent less time in the hospital and had a better quality of life.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Rosuvastatin in older patients with systolic heart failure
Article Abstract:
The results of clinical trial conducted by comparing rosuvastatin with placebo in elderly patients with systolic, ischemic heart failure are reported. Rosuvastatin was not effective as a therapy for heart failure, but was found to play significant role in reducing levels of both low-density lipoprotein cholesterol and high-sensitivity C-reactive protein.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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Cost effectiveness of simvastatin treatment to lower cholesterol levels in patients with coronary heart disease
Article Abstract:
Simvastatin appears to be cost-effective treatment for patients with heart disease. Simvastatin lowers cholesterol levels. Researchers used data from a Scandinavian study to estimate the cost effectiveness of simvastatin treatment according to age, sex, and cholesterol value prior to treatment. Direct cost savings from the reduction in costs associated with heart attacks ranged from $3,800 per year of life to $27,400, although savings disappeared among the elderly when the indirect costs of lost productivity were factored in. Results do not apply to prevention of heart disease.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
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