Intrauterine infection and preterm delivery

Article Abstract:

Many premature births may be caused by an infection in the uterus. Infection is common in women who deliver before 30 weeks but rare in those who deliver between 34 and 36 weeks. Bacteria may descend into the uterus from the Fallopian tubes or may ascend from the vagina. If they enter the fetal membranes, they cause an immune response that can rupture the membranes. Many pregnant women with uterine infections have no symptoms, making it very difficult to treat. However, any pregnant woman whose membranes rupture prematurely should probably receive antibiotics.

Infection, Causes of, Complications and side effects, Bacterial infections, Premature rupture of membranes, Premature rupture of the membrane, Uterus

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Endometrial microbial colonization and plasma cell endometritis after spontaneous or indicated preterm versus term delivery

Article Abstract:

A study was undertaken to determine whether endometrial microbial colonization and plasma cell endometritis is increased after spontaneous versus indicated preterm delivery or a spontaneous term delivery. Results showed that microbial colonization of the endometrium and plasma cell endometritis are similar 3 months after spontaneous or indicated preterm or term births.

United States, Science & research, Research, Usage, Premature labor, Endometritis, Premature labour, Microbiological techniques (Diagnosis)

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Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery

Article Abstract:

An elevated interleukin-6 level in second-trimester amniotic fluid may predict premature delivery. Interleukin-6 in amniotic fluid indicates inflammation in the uterus. Researchers compared amniotic fluid interleukin-6 levels in 290 pregnant women who delivered before 34 weeks' gestation and 290 women who delivered at term. Interleukin-6 levels were nearly twice as high in the second trimester in women who delivered early. Infection in the upper genital tract may cause interleukin levels to rise, increasing the risk of preterm delivery.

Analysis, Physiological aspects, Amniotic fluid, Interleukin-6, Chorioamnionitis

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