Immunogenetics of HTLV-I/II and associated diseases

Article Abstract:

Infections from human T-lymphotropic virus I (HTLV-I) and II (HTLV-II) appear to occur more frequently in people with certain histocompatibility types. HTLV-I infection can lead to adult T cell leukemia (ATL) and tropical spastic paraparesis (TSP). In a study of Japanese patients, those with ATL were more likely to have HLA-A26, B61 and DR9 and less likely to have HLA-A24, and Cw1 compared to healthy volunteers. Those with TSP were more likely to have HLA-Cw7, B7 and DR1. This could explain why different ethnic groups are more susceptible to these infections.

Health aspects, Genetic aspects, HLA histocompatibility antigens, HLA antigens, HTLV-I infections

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Risk factors for basal cell carcinoma of the skin in men: results from the health professionals follow-up study

Article Abstract:

Male health professionals and their risk of basal cell carcinoma of the skin were surveyed. Personal characteristics, exposure to sunlight, and outdoor habits or geographic location were associated with cancer risk.

Risk factors, Surveys, Diseases, Medical personnel, Skin, Men, Radiation effects, Skin, Effect of radiation on the, Basal cell carcinoma

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