Factors influencing the risk of infection with human immunodeficiency virus in homosexual men, Denver 1982-1985

Article Abstract:

Factors affecting the risk of AIDS infection were studied in 216 homosexual men. Forty had neither AIDS symptoms nor traces of the AIDS virus in their blood; twenty had the virus in their blood but no symptoms. Sixty-six had generalized disease of the lymph nodes (return disease-fighting white blood cells to the blood) and 37 had problems that often appear prior to full-blown AIDS (AIDS-related complex, ARC). Fifty-three had AIDS itself. (A person can have the virus in their blood for a long time before ARC or AIDS develops.) The risk of contracting the AIDS virus was increased by starting regular sexual intercourse with a male partner at a young age, by anal intercourse with ejaculation, by sexual contact with someone with AIDS or ARC and by a history of hepatitis B. Although the men with AIDS or ARC had no more sexual partners and engaged in anal sex no more often than the uninfected men at the time of the study, it is presumed that they probably did at the time of infection. It was concluded that AIDS-infected homosexual men who have actually developed AIDS or ARC have become less sexually active and that the virus is being spread to a greater extent by relatively healthy men.

Sexual behavior, HIV (Viruses), HIV, AIDS (Disease), Immunologic diseases, AIDS virus carriers, HIV carriers, AIDS-related complex

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Anal human papillomavirus infection among homosexual and bisexual men: prevalence of type-specific infection and association with human immunodeficiency virus

Article Abstract:

HIV-positive homosexual and bisexual men are likely to have anal infections with cancer-causing varieties of the human papillomavirus (HPV), the cause of genital warts. A group of 93 HIV-positive and 116 HIV-negative homosexual or bisexual men have been examined every six months since 1988. Overall, 61% of HIV-positive and 17% of HIV-negative men tested positive for anal HPV. Among HIV-positive men, the prevalence of HPV increased as CD4 counts decreased. HIV-positive men were 3.5 times more likely to test positive for HPV than HIV-negative men. HPV types 16 18, the types most strongly associated with cancer, accounted for over half the infections. It is thought that the increasing prevalence of HPV with declining CD4 cell counts is due to the decreasing ability of the immune system to keep the latent virus in check. With increasing lifespan among HIV patients, it is possible that anal cancer may become another opportunistic disease among homosexual bisexual men.

Complications and side effects, Physiological aspects, Papillomavirus infections

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Human immunodeficiency virus seroprevalence and risk assessment of a homeless population in Denver

Article Abstract:

Homeless people in certain U.S. cities may not have a high rate of HIV infection but they may engage in behaviors that put them at risk for HIV infection. Researchers in Denver, Colorado conducted a survey of 2,934 homeless people attending a primary care clinic for the homeless regarding HIV risk behaviors and personal data. Twenty-six people in this group were HIV-positive, a rate of 0.9%. Injection drug users, men who were homosexual or bisexual, and men with an at-risk partner had higher rates of HIV infection.

Risk factors, Homeless persons, HIV seroprevalence

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