Chorionic villus sampling before multifetal pregnancy reduction
Article Abstract:
Chorionic villus sampling appears to be safe when done before a multiple pregnancy is reduced. Chorionic villus sampling is done to determine if any of the fetuses has a genetic disorder. If so, that fetus would be aborted, leaving the healthy fetuses to continue to term.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
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First-trimester transabdominal multifetal pregnancy reduction: a report of two hundred completed cases
Article Abstract:
The number of fetuses carried by a woman can be safely reduced by injecting selected fetuses with potassium chloride. This procedure has few significant side effects to the mother or remaining fetuses. Of 200 women pregnant with three or more fetuses who underwent this procedure, 181 delivered one or more live infants. Infertility therapy accounted for 199 of the pregnancies. Almost 90% of the procedures were performed on women between the 11th and 13th weeks of pregnancy. The women were seen as outpatients and all received prophylactic antibiotics. An ultrasound examination identified the location and viability of the fetuses. The ultrasound was also used to guide the placement of the needle that injected the potassium chloride and to monitor the cessation of heart activity. Women were monitored in-house for a few hours after the procedure. They were then discharged and told to limit their activities for 48 hours. Nineteen of the women miscarried the remaining fetuses. Three pregnancies were lost within four weeks of the procedure, six in the four-to-eight weeks after the procedure and 10 were lost more than eight weeks later.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1993
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The current status of multifetal pregnancy reduction
Article Abstract:
Selective reduction of triplet pregnancies to twins may be fairly safe in light of the increased risks of preterm birth of triplets. Prevention of multifetal pregnancies in the first place is much more preferable to selective reduction after assisted reproduction treatments. Selective reduction of multifetal pregnancies to twins can reduce the risk of preterm birth and of losing the entire pregnancy, but may still result in loss of the entire pregnancy. Selective reduction may be warranted in triplet pregnancies as well as in pregnancies with four or more fetuses. The transvaginal approach where potassium chloride is injected into the fetus's chest appears to be the most effective method of selective reduction with a pregnancy loss rate of 9%. Selective reduction should not become a backup for infertility providers.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
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- Abstracts: Two hundred ninety consecutive cases of multifetal pregnancy reduction: Comparison of the transabdominal versus the transvaginal approach
- Abstracts: Treatment of severe congenital diaphragmatic hernia by fetal tracheal occlusion: clinical experience with fifteen cases
- Abstracts: Further observations on the fetal inflammatory response syndrome: a potential homeostatic role for the soluble receptors of tumor necrosis factor alpha