Five-year results of iliac and femoropopliteal angioplasty in diabetic patients
Article Abstract:
Percutaneous transluminal angioplasty (PTA) is a procedure used in treating vascular disease, both in the periphery and in the cardiopulmonary system. It involves inserting a deflated balloon at the tip of a catheter into the narrowed or blocked vessel and inflating the balloon to open the vessel. This study examined the long-term effectiveness of PTA in treating peripheral vascular disease in diabetic patients, have are at increased risk for developing vascular disease. PTA was performed on 127 arteries (70 iliac arteries, 41 femoral arteries, and 16 popliteal arteries) found in the legs of 97 diabetic patients. Patients were evaluated for both initial and long-term outcomes of treatment. Initial outcome was judged to be either a technical and clinical success, a technical but not a clinical success, or a technical failure. PTA in the iliac arteries was technically successful in 66 (94 percent) of cases and clinically successful in 62 of the 70 cases (89 percent). Patency rates (the proportion of arteries that were completely open) at five years following iliac PTA were 34 percent for all cases that were initially successful, 76 percent for cases in which initial runoff was good (i.e. where there were two or three normal calf arteries), and 20 percent for those in which initial runoff was poor (where there were no normal calf arteries). Patency rates at five years for femoral arteries were 14 percent for the initially successful cases, 46 percent in which runoff was initially good, and 8 percent in which runoff was initially poor. A number of patients had gangrene in their legs and underwent PTA in an attempt to save avoid amputation. Five-year patency rates for arteries in these patients were 29 percent for iliac, 7 percent for femoral, and 0 percent for popliteal arteries. Results showed that five-year patency rates after PTA was performed in arteries of the legs of diabetic patients were similar to those of nondiabetic patients when the initial runoff was good. For diabetic patients with more severe vascular disease, patency rates were much lower. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Radiology
Subject: Health
ISSN: 0033-8419
Year: 1990
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Cystic fibrosis: MR imaging of the pancreas
Article Abstract:
Cystic fibrosis (CF) is an inherited disease that affects the exocrine glands (which secrete enzymes and other substances through ducts). The pancreas may be severely compromised. Common complications of CF include respiratory infections and difficulty digesting food. Ultrasound (US; the use of high-frequency sound waves) and computed tomography (CT; computer generated images obtained through the use of X-ray) are two imaging techniques that have been used to examine the pancreas of CF patients. It has been reported that US is not sensitive enough to detect pancreatic abnormalities and CT, although highly sensitive, exposes young patients to radiation. The use of magnetic resonance (MR) imaging, which does not involve radiation exposure, was assessed as a means of detecting pancreatic abnormalities in patients with CF. Seventeen adult CF patients, 14 with abnormal pancreatic function and 3 with normal function, were examined with MR; 8 of the 14 were also examined by CT. The 14 patients who had known pancreatic problems showed abnormalities on both MR and CT scans. In the three patients with normal pancreatic functioning, MR findings were normal in two. In the 15 patients showing pancreatic abnormalities, three patterns were found. In nine patients, the pancreas appeared enlarged and normal tissue was completely replaced by fatty tissue. In five patients, the pancreas appeared atrophied (decreased or shrunken in size), with some normal tissue replaced by fatty tissue. In one case, the pancreas was atrophied, but no fat tissue replacement was seen. These results indicate that MR is as sensitive as CT in imaging the pancreas and revealing pancreatic abnormalities associated with CF. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Radiology
Subject: Health
ISSN: 0033-8419
Year: 1991
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