Heart Valve Disorders and Appetite-Suppressant Drugs
Article Abstract:
Most people who took the diet pills fenfluramine or dexfenfluramine will probably not develop serious heart valve disease. These drugs were withdrawn by the manufacturer in 1997 after the FDA reported an increased risk of heart valve disease in people who took the drugs. A study published in 2000 confirmed this risk, but found that most cases of heart valve disease were mild. Other studies have shown that the heart valves may return to normal when the drugs are discontinued. People who took high doses of the drug for more than three months have the highest risk of valve disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Contemporary clinical profile and outcome of prosthetic valve endocarditis
Article Abstract:
A study was conducted to find the characteristics and outcome of prosthetic valve endocarditis (PVE), and to determine prognostic factors associated with in-hospital mortality. It was revealed that PVE accounted for a high percentage of all cases of infective endocarditis in many regions of the world, and complications of PVE strongly predict in-hospital mortality.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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Impact of valve surgery on 6-month mortality in adults with complicated, left-sided native valve endocarditis: a propensity analysis
Article Abstract:
Heart valve replacement is more effective than medication for treating a bacterial infection of the heart called endocarditis, according to a study of 513 people. Surgery was especially beneficial for patients with congestive heart failure. Six-month mortality rates were 50% to 80% lower in the patients who had surgery compared with those treated with drugs.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
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