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Hereditary Hemochromatosis

Article Abstract:

An expert panel convened by the Centers for Disease Control and Prevention (CDC) and the National Human Genome Research Institute has recommended against widespread screening for hemochromatosis. This hereditary disease is characterized by elevated blood iron levels that can damage the liver. The panel reviewed all the evidence on hemochromatosis, including the gene that has been linked to the disease. Uncertainty about the frequency of the gene in the general population and how asymptomatic people who test positive should be treated led the panel to reject population screening until more is known about its effectiveness.

Author: Adams, Paul C., Burke, Wylie MD, PhD, Thomson, Elizabeth MS, RN, Chori, Muin J. MD,, McDonnell, Sharon M. MD, MPH, Press, Nancy PhD, Barton, James C. MD, Beutler, Ernest MD, PhD

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Hereditary Hemochromatosis

Article Abstract:

An expert panel convened by the Centers for Disease Control and Prevention (CDC) and the National Human Genome Research Institute has recommended against widespread screening for hemochromatosis. This hereditary disease is characterized by elevated blood iron levels that can damage the liver. The panel reviewed all the evidence on hemochromatosis, including the gene that has been linked to the disease. Uncertainty about the frequency of the gene in the general population and how asymptomatic people who test positive should be treated led the panel to reject population screening until more is known about its effectiveness.

Author: Adams, Paul C., Burke, Wylie MD, PhD, Thomson, Elizabeth MS, RN, Chori, Muin J. MD,, McDonnell, Sharon M. MD, MPH, Press, Nancy PhD, Barton, James C. MD, Beutler, Ernest MD, PhD

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

User Contributions:

Comment about this article or add new information about this topic:

Subjects list: Evaluation, Diagnosis, Medical screening, Health screening, Hemochromatosis

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Abstracts: Hereditary Hemochromatosis

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