High-level quinolone resistance in Neisseria gonorrhoeae: a report of two cases
Article Abstract:
Two cases of resistance to quinolone antibiotics by Neisseria gonorrhoeae may suggest the need for surveillance of new strains of N. gonorrhoeae. Quinolone antibiotics are the usual treatment for N. gonorrhoeae. The two cases involved men who had had sexual contact with local women while in the Philippines. The cases were diagnosed after the men sought medical care in Australia. Ciprofloxacin and doxycycline treatments did not cure the first patient. He was finally cured with daily injections of ceftriaxone for five days. The second patient was not cured by perfloxacin or quinolone. He was given ceftriaxone injections and spectinomycin, which cured him. Researchers identified two slightly different strains of N. gonorrhoeae from the men.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1995
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Continuing evolution of the pattern of quinolone resistance in Neisseria gonorrhoeae isolated in Sydney, Australia
Article Abstract:
The growth of quinolone-resistant Neisseria gonorrhoeae (QRNG) infections in Sydney, Australia, may be associated with heterosexual transmission between prostitutes and their clients. Gonorrhea infections resistant to quinolone antibiotic drugs have become more common, and 219 resistant infections were identified in Sydney from 1995 through 1997. Determination of the bacterial strains causing the infections indicate that resistant infections have changed from sporadic occurrences of infection from foreign sources to local transmission by heterosexual sex with prostitutes.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1998
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Quinolone-resistant Neisseria gonorrhoeae isolated in Sydney, Australia, 1991 to 1995
Article Abstract:
Australian cases of quinolone-resistant Neisseria gonorrhoeae (QRNG) may have been imported from Asia. Researchers analyzed the types of QRNG in Sydney, Australia from 1991 to 1995 and compared them with QRNG from 1984 to 1990. Few cases of gonorrhea in Sydney were found to resist quinolone before 1991. Beginning in 1991, quinolone resistance grew slowly until the last six months of the study when it expanded quickly. Most types of QRNG came from Asian travellers. Levels of resistance have increased recently to the point where quinolones cannot cure some QRNG strains.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1996
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