Human T cell leukemia virus type I (HTLV-I) molecular genotypes and disease outcome

Article Abstract:

A mutation in the tax gene of the human T cell leukemia virus type I (HTLV-I) may predispose people infected with the virus to develop tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). This was demonstrated by comparing the genetic structure of the virus in two groups of HTLV-I-infected people: Japanese and Columbians. Columbians with TSP/HAM were more likely to have a mutation in the tax gene than Japanese with adult T cell leukemia. The incidence of TSP/HAM is higher in Columbia than Japan even though the incidence of HTLV-I infection is lower.

Gene mutations, Gene mutation, Genetic aspects, HTLV-I (Virus), Paraparesis, Tropical spastic, Tropical spastic paraparesis

---

HIV-1 pol sequences from India fit distinct subtype pattern

Article Abstract:

A new subtype of HIV-1 has been identified in India. It was discovered by sequencing the viral pol gene in blood samples taken from 5 HIV-positive individuals in various regions of India. Both pol and env genes indicate that the virus belongs to the C subtype. This indicates that HIV-1 was introduced into India fairly recently. HIV infection was first reported in India in 1986. It is most common in urban areas and is transmitted primarily by heterosexual sex.

HIV (Viruses), HIV, India, Viruses, Identification and classification, Evolution (Biology)

---

Similar abstracts:

• Abstracts: High endemicity of human T-cell lymphotropic virus type 1 among pregnant women in Peru. Differential upregulation of CD38 on different T-cell subsets may influence the ability to reconstitute CD4(super +) T cells under successful highly active antiretroviral therapy
• Abstracts: Implications of the latest NICE Parkinson's disease guidance. Sources of a broad range of services
• Abstracts: Silence masks prevalence of fecal incontinence. Evidence-based guidelines needed for osteoporosis screening and treatment
• Abstracts: A two-year clinical evaluation of pit and fissure sealants placed with and without air abrasion pretreatment in teenagers
• Abstracts: Poverty, oral health and human development: Contemporary issues affecting the provision of primary oral health care

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.