Projected Cost-effectiveness of Pneumococcal Conjugate Vaccination of Healthy Infants and Young Children
Article Abstract:
The pneumococcal conjugate vaccine would be cost-effective in babies if the cost of the vaccine was less than $50 per dose. This was the conclusion of researchers who evaluated the cost-effectiveness of the vaccine on a hypothetical group of 3.8 million babies. Vaccination would prevent more than 53,000 cases of pneumonia, 1 million cases of otitis media, and 116 deaths from pneumococcal infection.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Prevalence and incidence of adult pertussis in an urban population
Article Abstract:
Pertussis appears to be fairly common among adults. The incidence of pertussis, or whooping cough, has increased substantially in the US despite the use of the DPT vaccine. Researchers tested blood samples of 153 adults with chronic cough for antibodies to pertussis toxin. Nineteen (12%) had high antibody levels, indicating that they had pertussis. Only nine reported childhood immunizations and many were not documented. A review of the medical records of all 153 adults revealed that none of the doctors they saw considered pertussis as a possible diagnosis. The incidence of pertussis based on this data was 176 cases per 100,000 person-years, which is comparable to the incidence of peptic ulcer in the adult population. Adults with pertussis could pass the infection on to infants and children. It may be necessary to give children a booster shot sometime after the age of 7.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1996
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Immunization Levels Among Premature and Low-Birth-Weight Infants and Risk Factors for Delayed Up-to-Date Immunization Status
Article Abstract:
Many very-low-birth-weight babies are not being vaccinated in a timely manner. In a study of 6,832 low-birth-weight and premature babies, those with very low birth weights were less likely to be vaccinated at all ages up to two years compared to heavier infants. The percentage of premature infants overall who were adequately vaccinated was close to that of normal-birth-weight infants, but the very-low-birth-weight babies lagged behind. Well-child preventive care was linked to immunization.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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