Improved graft survival after renal transplantation in the United States, 1988 to 1996
Article Abstract:
The survival of kidney transplants has increased since 1988. Between 1988 and 1996, the half-life for kidney transplants increased from 12.7 years to 21.6 years. Ninety-four percent of kidney transplants from a living donor survived at least one year in 1996, compared to 89% in 1998. For kidneys from cadavers, the one-year survival rate increased from 76% to 88%. It is critical to make kidney transplants last as long as possible, because the number of people who need one exceeds the supply.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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The natural history of chronic allograft nephropathy
Article Abstract:
Almost all patients who receive a kidney transplant will develop disease in the transplanted kidney, according to a study of 120 patients with type 1 diabetes who received a kidney-pancreas transplant. Ten years after the operation, almost all the patients had disease in the transplanted kidney and 59% had severe kidney disease. This damage is irreversible, and may eventually cause the kidney to fail.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection
Article Abstract:
Mesenchymal cells from an organ recipient can travel to the transplanted organ and begin the process of graft rejection. Researchers were able to determine this by looking for the male Y chromosome in kidney tissue taken from men and women who had received a kidney from a donor of the opposite sex.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
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