Incidence of end-stage renal disease in patients with type 1 diabetes
Article Abstract:
A study is conducted to estimate the long-term risk of developing end-stage renal disease (ESRD) and to assess how age at diagnosis of diabetes, time period of diagnosis, and sex affect the risk. The study reveals that the forecasting of type 1 diabetes in connection with ESRD has improved during the past few decades, and children diagnosed as having diabetes before age 5 years have the most favorable prognosis.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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TCF7L2 polymorphisms and progression to diabetes in the diabetes prevention program
Article Abstract:
A study was conducted to examine whether the two most strongly associated variants of transcription factor 7-like 2 gene (TCF7L2) predict the progression to diabetes in persons, with impaired glucose tolerance, enrolled in the Diabetes Prevention Program. The risk-conferring genotypes in TCF7L2 are linked with impaired beta-cell function and not with insulin resistance.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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Isolated pancreas transplantation for type 1 diabetes: a doctor's dilemma
Article Abstract:
A pancreas transplant may not benefit many patients with type 1, or juvenile onset, diabetes, according to a study published in 2003. Doctors should be very cautious when attempting this treatment and should select only those patients most likely to benefit from the procedure. Improvements in the care of diabetes may eliminate the need for this operation.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
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