Increase in age at onset of rheumatoid arthritis in Japan over a 30 year period

Article Abstract:

People in Japan are developing rheumatoid arthritis (RA) much later in life but the reasons for this are not clear. Researchers analyzed the records of patients diagnosed with RA between 1960-1965 and 1985-1990. The age at which patients first presented with symptoms of RA rose from the 20's and 30's in 1960-1965 to the 40's and 50's in 1985-1990. However, the severity of the disease remained about the same. Many changes in lifestyle, socioeconomic status and public health occurred in the 30 years between the two time periods. Further research may reveal the reasons for this phenomenon.

Demographic aspects, Age factors in disease, Disease age factors

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Polymorphic CAG repeats of the androgen receptor gene and rheumatoid arthritis

Article Abstract:

The authors investigated the relationship of of the genetic chemistry of certain androgen receptors and the onset of rheumatoid arthritis. They found a relationship between high levels and onset of rheumatoid arthritis at a younger age in makes, suggesting a definite connection.

Physiological aspects, Androgens

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Changes in the incidence and prevalence of rheumatoid arthritis in Kamitonda, Wakayama, Japan, 1965-1996

Article Abstract:

The incidence of rheumatoid arthritis has decreased significantly in Japanese women but not in Japanese men. Between 1965 and 1996, the incidence dropped more than 50%, but this was almost exclusively in women.

Japan, Statistics

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