Interleukin 2 Treatment for HIV Infection
Article Abstract:
More research is needed before interleukin-2 (IL-2) treatment can be recommended to HIV patients. A study published in 2000 showed that HIV patients who received traditional AIDS drugs plus IL-2 had greater immune recovery than those who took AIDS drugs only. However, 54% of the patients taking AIDS drugs plus IL-2 developed side effects compared to only 16% of those taking AIDS drugs only. Researchers also need to determine whether the modest immune recovery has any health benefits. One study showed that patients with severe immunosuppression did not benefit from IL-2 treatment.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Initiating Antiretroviral Therapy During HIV Infection: Confusion and Clarity
Article Abstract:
Doctors may be able to avoid treating some HIV patients with AIDS drugs until the patient's CD4 T cell count drops to 200. Two studies published in 2001 show that patients with CD4 T cell counts of 200 or more will respond to treatment and have a low risk of progression to AIDS and death. Waiting to begin treatment can spare the patient from the severe side effects of many AIDS drugs.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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Structured Treatment Interruptions for the Management of HIV Infection. (Special Communication)
Article Abstract:
HIV patients who are in the early stages of the infection may benefit from stopping treatment periodically. This will reduce the number of side effects they experience. However, more research is needed to determine whether sicker patients benefit from treatment interruptions.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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