Interstitial radiotherapy for the treatment of advanced or recurrent vulvar and distal vaginal malignancy

Article Abstract:

Advanced or recurring cancers of the vulva and vagina (introital malignancies) are uncommon. Information regarding radical radiotherapy for these conditions is limited. The experience with interstitial radiotherapy needles in the treatment of advanced or recurrent introital cancer is reviewed. Ten patients received primary therapy, either removal of the tumor or radiation therapy. Interstitial radiotherapy was applied through needles to increase the tumor dose, with or without teletherapy, radiation administered by a machine positioned away from the patient. At the 28-month follow-up, nine patients were alive and one patient had died from a radiotherapy complication. Two patients developed recurrent disease combined with severe radionecrosis, a complication of radiotherapy causing severe tissue death, 13 and 47 months after therapy began, respectively. Seven patients remain disease-free. A total of six patients developed severe necrosis between 6 to 26 months after beginning radiotherapy. Although the use of interstitial radiotherapy needles and teletherapy was effective, it was associated with a high degree of tissue necrosis. Patients with inoperable tumors should have combined external radiation and chemotherapy until surgical removal is feasible. Only if the disease persists should interstitial needles be used. (Consumer Summary produced by Reliance Medical Information, Inc.)

Radiotherapy, Squamous cell carcinoma, Radioisotope brachytherapy, Brachytherapy, Vulvar cancer, Vaginal cancer

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Subcutaneous management of vertical incisions with 3 or more centimeters of subcutaneous fat

Article Abstract:

The most appropriate management of the subcutaneous tissue of midline vertical incisions with 3 cm or more of subcutaneous fat is determined. The findings reveal that the suture approximation or drainage of the subcutaneous tissues of women with 3 cm or more subcutaneous fat measured in midline vertical incisions have resulted in no significant change in the incidence of overall wound complications or superficial wound disruption.

Women, Risk factors, Obesity, Wounds and injuries, Women's health, Wound care

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Upper vaginectomy for the treatment of vaginal intraepithelial neoplasia

Article Abstract:

The use of upper vaginectomy for the treatment of vaginal intraepithelial neoplasia (VAIN) is evaluated. Upper vaginectomy was found to be efficacious for the treatment of VAIN and also led to the diagnosis of occult invasive cancer in 12 percent of the patients.

United States, Medical Instruments and Supplies, Medical Equipment and Supplies Manufacturing, Pediatric & Obstetrical Equip, Usage, Vaginal diseases, Obstetrics, Obstetrical equipment

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