Late symptoms after pregnancy-related deep vein thrombosis

Article Abstract:

Deep vein thrombosis (DVT) is caused by a clot blocking the flow of blood within a deep vein. Although the condition is relatively uncommon, it can occur during pregnancy and after delivery. The condition can be life-threatening if the blood clot dislodges and travels to other areas of the body. Some studies have found that women who suffer DVT during pregnancy have evidence of the disease 3 to 13 years later. The long-term consequences of DVT were studied in 104 women who experienced DVT during pregnancy or within 42 after birth (puerperium). The women were asked for details of their pregnancy, further episodes of thromboembolism, present symptoms, and treatments used. All of the women had DVT diagnosed by objective tests that assessed the blood circulation in the legs. All but one women received heparin therapy, a clot dissolving agent. In the group of women with DVT during pregnancy, 78 percent had complaints such as swelling, pain, cramps, discoloration and itching eczema. Of the women with DVT at puerperium, 70 percent had complaints. All of the patients who developed leg ulcers had DVT during pregnancy (4 percent). More of the women with DVT during pregnancy wore compression bandages than the puerperal women with DVT. The number of thrombotic episodes was related to severity of symptoms, and treatment was not effective in preventing long-term complications of DVT. The results suggest that women with pregnancy-related thrombosis are at increased risk for future venous insufficiency and ulceration. (Consumer Summary produced by Reliance Medical Information, Inc.)

Care and treatment, Risk factors, Thromboembolism, Thrombosis, Deep vein, Deep vein thrombosis

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Infection with the Puumala virus in pregnancy: case report

Article Abstract:

A 29-year-old woman who was pregnant for the second time developed a high fever, headache, abdominal pain and muscle pain in her seventeenth week of pregnancy. Exploratory surgery lead to the removal of a healthy appendix. After the operation, the patient had elevated levels of protein in her urine, and toxins that are produced during kidney failure were detected in her blood. Blood tests confirmed that the patient was infected with the Puumala virus, resulting in nephropathia epidemica, a virus-induced kidney disease. The woman was well four months later, and a healthy boy was born at term. The child's blood was tested to see if he had developed antibodies to the Puumala virus. Viral antibodies were found, but were thought to be passive antibodies obtained from the mother's immune system rather than antibodies produced by the fetus. The child was symptom-free at five months of age. Nephropathia epidemica is included in the group of diverse severe epidemic viral diseases (usually found in tropical climates) known as hemorrhagic fever with renal syndrome. The viruses are carried by rodents and contracted by breathing in dust from the rodents' contaminated feces or urine. In some cases, maternal infection with these viruses can pass through the placenta to infect the fetus, causing a high rate of miscarriage. Human-to-human transmission has not been reported. (Consumer Summary produced by Reliance Medical Information, Inc.)

Case studies, Kidney diseases, Hemorrhagic fever, Hemorrhagic fevers

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