Management of women with one abnormal oral glucose tolerance test value reduces adverse outcome in pregnancy

Article Abstract:

A diagnosis of gestational diabetes mellitus, a form of glucose intolerance that occurs during pregnancy, is made on the basis of two abnormal results of a glucose tolerance test (GTT). To determine whether a single abnormal GTT resulted in a poor pregnancy outcome, 126 women with one abnormal test value were compared to 146 women with normal values. The abnormal GTT women were randomly divided into two groups, one treated with a strict diabetic program with diet control and insulin, the hormone essential for sugar metabolism, the other group untreated but measured for blood sugar periodically. There were significant differences in blood glucose levels between the treated and untreated groups. It was found that the untreated group had a higher incidence of larger infants and other metabolic complications commonly occurring in patients with gestational diabetes. There were no major differences between the normal and the treated groups. It is suggested that the definition of gestational diabetes be reassessed and that treatment should be offered to patients having one abnormal GTT.

Standards, Glucose tolerance tests, Glucose tolerance test

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Overweight and obese in gestational diabetes: The impact on pregnancy outcome

Article Abstract:

The relationship between prepregnancy weight, treatment modality level of glycemic control, and pregnancy outcome is investigated. The results revealed that obese women with body mass index (BMI) greater than or equal to 30 with gestational diabetes (GDM), achievement of targeted levels of glycemic control is associated with enhanced outcome only in women treated with insulin.

United States, Risk factors, Obesity, Pregnancy, Complications of, Pregnancy complications

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The postprandial glucose profile in the diabetic pregnancy

Article Abstract:

A novel approach that provides continuous measurement of blood glucose is used to determine postprandial glucose profile in the diabetic pregnancy. The results indicate that the time interval for postprandial glucose peak in diabetic pregnancy is approximately 90 minutes after meals throughout the day and is not affected by level of glycemic control.

Pregnancy, Glucose, Dextrose

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