Massive fetomaternal hemorrhage treated with serial combined intravascular and intraperitoneal fetal transfusions

Article Abstract:

Fetomaternal hemorrhage may be treated with success using intraperitoneal and intravascular transfusions. A 26-year-old pregnant woman was referred for evaluation because her uterus was larger than the length of pregnancy should indicate. Ultrasound scans showed a fetus with gross swelling of the body. Severe fetal anemia was diagnosed through blood tests. The fetus received blood transfusions five times during a 24-day period using both intraperitoneal and intravascular techniques, and one platelet transfusion for thrombocytopenia. The combination apparently provided the fetus with an extra reserve of hemoglobin. The baby was born 26 days after the initial event with a distended abdomen and swelling of the scalp, but did well after ventilation and postpartum transfusions were unnecessary.

Care and treatment, Hemorrhage, Blood transfusion, Fetal diseases

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Successful treatment of acute myocardial infarction during pregnancy with tissue plasminogen activator

Article Abstract:

Tissue plasminogen activator (tPA) may be a beneficial treatment for pregnant heart attack patients. A 30-year-old woman who was pregnant with her third child experienced a heart attack at 21 weeks of pregnancy. She smoked and had diet-controlled gestational diabetes. The heart attack did not harm the fetus. Intravenous tPA therapy resolved her chest pain and some of the electrocardiogram abnormalities. She was delivered of a baby boy by cesarean section at 33 weeks of pregnancy. tPA may be safely used in pregnant women because of its short half-life and inability to cross the placenta.

Drug therapy, Heart attack, Pregnant women, Tissue plasminogen activator

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Persistent cerebrovascular changes in postpartum preeclamptic women: a Doppler evaluation

Article Abstract:

Women who have had preeclampsia may have constriction of the small blood vessels in the brain persisting for longer than 12 weeks after giving birth. Preeclampsia is a serious complication of pregnancy characterized by blood vessel constriction throughout the body. Measurements indicating vascular constriction were obtained 6 weeks postpartum on 19 preeclamptic women, and on 8 preeclamptic women 12 weeks after giving birth. Large vessel constriction was not seen, compared to normal women, but small vessel constriction in the preeclamptic women persisted at 12 weeks postpartum.

Cerebral circulation, Diagnosis, Measurement, Physiological aspects, Preeclampsia, Vasoconstriction

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