Neutrophil and monocyte beta(sub2)-integrin expression in maternal and fetal blood
Article Abstract:
Fetal white blood cells mature in their immunological capability over the course of pregnancy. Pregnancy also enhances the capability of maternal white blood cells. Blood samples were drawn from 114 women with pregnancies ranging from 6 to 40 weeks in length and from 25 nonpregnant adults. Fetal blood samples were drawn from the umbilical cords of 159 fetuses. Umbilical cord blood was also drawn from 14 newborns after term elective cesarean section. Measurements were made of the activity of beta2-integrins, a family of molecules present on the surface of neutrophil and monocyte white blood cells. These molecules affect many of the immunoprotective functions of monocytes and neutrophils. The density of most types of beta2-integrins increased as the pregnancy progressed. Not all types reached adult values by term. Density also increased among pregnant women compared with nonpregnant controls, but there was no correlation with length of gestation. This may explain the susceptibility of preterm infants and even term newborns to infection.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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The newborn screening educational gap: What prenatal care providers do compared with what is expected
Article Abstract:
A study is carried out to examine prenatal care provider's knowledge of, attitudes towards, and barriers for providing information about newborn screening and tandem mass spectrometry screening. The state needs to improve communication with providers and the public about newborn screening as pregnant women and state professionals rely on prenatal care providers to educate pregnant women about newborn screening, but many providers do not appear to view it as part of their responsibility.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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