Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine
Article Abstract:
Measuring the amount of perforin and granzyme B in cells in urine samples may detect organ transplant recipients whose transplanted organ is being rejected by the patient's immune system. These two proteins are produced by T cells that destroy other cells.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
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Messenger RNA for FOXP3 in the urine of renal-allograft recipients
Article Abstract:
Levels of messenger RNA for FOXP3, a specification and functional factor for regulatory T lymphocytes, and mRNA for CD25, CD3E, perforin, and 18S ribosomal RNA are measured with a kinetic, quantitative polymerase-chain-reaction assay. Results reveal that measurement of FOXP3 mRNA in urine might offer a noninvasive means of improving the prediction of outcome of acute rejection of renal transplants.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
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HLA-mismatched renal transplantation without maintenance immunosuppression
Article Abstract:
A new approach for bone marrow and kidney transplant of a patient with renal disease with a HLA-mismatched living related donor is discussed. The transplantation is found to be extremely effective, as it leads to the discontinuation of the immunosuppressive therapy.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
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- Abstracts: Anthropometry and methods of body composition measurement for research and field application in the elderly. Multi-component body composition models: recent advances and future directions
- Abstracts: The influence of fish, meat and polyunsaturated fat intakes on platelet phospholipid polyunsaturated fatty acids in male Melbourne Chinese and Caucasian