Physician Interpretations and Textbook Definitions of Blinding Terminology in Randomized Controlled Trials
Article Abstract:
Many doctors are not clear about what constitutes single, double, and triple blinding in a research study and medical textbooks are not much help. This was the conclusion of researchers who surveyed 91 doctors and consulted 25 textbooks. In a research study, blinding means that one or more groups of people participating in the study do not know which patients receive which treatment.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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Comparison of 2 Methods for Calculating Adjusted Survival Curves From Proportional Hazards Models
Article Abstract:
Researchers should use the corrected group prognosis method for estimating patient survival curves rather than the mean of covariates method. The latter method can provide misleading data. Survival curves are generated to estimate the predicted survival of two or more groups of patients.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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Randomized trials stopped early for benefit
Article Abstract:
The epidemiology and reporting quality of randomized clinical trials (RCTs) involving interventions stopped early for benefit is evaluated. RCTs stopped early for benefits are becoming more common, often fail to adequately report relevant information about the decision to stop early and give implausibly large treatment effects.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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