Points of control in inflammation

Article Abstract:

This review delineates the complex set of interactions occurring between soluble factors and cells during an inflammatory response to traumatic, infectious, post-ischaemic, toxic or autoimmune injury. Research findings indicate that in most cases, the process leads to recovery from injury. However, when non-inflammatory conditions do arise they occur due to suppression of reactions leading to inflammatory stimuli.

Physiological aspects, Wounds and injuries, Injuries, Cellular signal transduction

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Aligning pharmaceutical innovation with medical need

Article Abstract:

The research and development (R&D), delivery of health care products and open access drug companies might spur innovation while improving science, widening the scope and stabilizing the funding of the public-private partnerships (PPPs). Financial incentive would come from registering patterns on track II and companies would strive to maximize access to such products through low pricing and low licensing.

Product development, Drugs & Pharmaceuticals, Pharmaceutical and Medicine Manufacturing, Government regulation, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Drugs, Metabolic Agents NEC, Metabolic Agents, Innovations, Pharmaceutical industry, Licensing, certification and accreditation

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TREM-1: a new regulator of innate immunity in sepsis syndrome

Article Abstract:

Research on the treatments for sepsis syndrome focuses on the control of innate immune response and inflammatory reactions. Possible therapies focus on the expression of an immunoglobulin molecule called 'triggering receptor expressed on myeloid cells' or TREM-1.

Research, Bacterial infections, Immunoglobulins, Immune response regulation

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