HPV DNA Testing of Self-collected Vaginal Samples Compared With Cytologic Screening to Detect Cervical Cancer

Article Abstract:

Testing self-collected vaginal swabs for human papillomavirus (HPV) might help identify women with cervical cancer in parts of the world where cervical cancer screening is not available. HPV infection has been linked to an increased risk of cervical cancer. Researchers tested self-collected vaginal swabs from 1,415 women for HPV in a settlement outside of Cape Town, South Africa. Nine cases of invasive cervical cancer were detected and 47 women had high-grade squamous intraepithelial lesions, which is a precursor of cervical cancer.

Testing, Papillomaviruses, Papillomavirus

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Two-stage cervical cancer screening: an alternative for resource-poor settings

Article Abstract:

A two-stage screening method for cervical cancer may be effective in countries that cannot afford expensive diagnostic tests. This was the conclusion of a study of 1,423 women from Cape Town South Africa, who had pelvic exams first, and other tests only if the doctor found an abnormality during the physical exam.

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Policy Analysis of Cervical Cancer Screening Strategies in Low-Resource Settings: Clinical Benefits and Cost-effectiveness

Article Abstract:

Direct visual inspection of the cervix and tests for human papillomavirus are cost-effective strategies for detecting cervical cancer in developing countries. Pap smears and the personnel necessary to examine the smears are not always available in these countries.

Health aspects, Developing countries

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