Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing

Article Abstract:

Study is conducted to evaluate the efficacy of first-line highly active antiretroviral therapy (HAART) guided by genotypic resistance testing by comparing treatment outcomes of patients with drug-sensitive HIV to outcomes of patients with primary resistance. HAART guided by resistance testing had similar efficacy in patients with primary drug resistance as compared with patients with wild-type virus.

Patient outcomes, HIV infection, HIV infections, Comparative analysis, Antiviral agents, Antiretroviral agents

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Switching to atazanavir improves metabolic disorders in antiretroviral-experienced patients with severe hyperlipidemia

Article Abstract:

The efficacy and change in lipid profile in patients with severe hyperlipidemia after switching to an atazanavir containing highly active antiretroviral therapy regimen is described. A switch to atazanavir that is proposed as a valuable option to improve atherogenic lipid profiles while maintaining virologic control results in a significant improvement in HIV therapy-induced hyperlipidemia.

Health aspects, Dosage and administration, Metabolic diseases, Atazanavir (Medication)

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Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death

Article Abstract:

An attempt is made to describe the clinical course and to determine survival duration in highly active antiretroviral therapy (HAART)-treated patients with HIV-associated progressive multifocal leukencephalopathy (PML). The main aim was also to identify risk factors for death and to evaluate the efficacy of cidofovir therapy in addition to HAART.

Science & research, Care and treatment, Research, Risk factors, Leukoencephalopathy, Progressive multifocal, Progressive multifocal leukoencephalopathy

Similar abstracts:

• Abstracts: HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia
• Abstracts: Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial

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