Protection of cynomolgus macaque against cervicovaginal transmission of SIVmac251 by the spermicide benzalkonium chloride
Article Abstract:
The spermicide benzalkonium chloride completely protected six macaque monkeys from infection by simian immunodeficiency virus (SIV) when used in a vaginal suppository. Six monkeys who were not treated all developed SIV infection. This virus is related to HIV but infects monkeys.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Fluctuations in HIV-1 viral load are correlated to CD4+ T-lymphocyte count during the natural course of infection
Article Abstract:
Researchers reject the hypothesis that fluctuations in viral load in the early stages of HIV infection randomly occur around a set point or underlying growth trend. Instead, they found that the fluctuations were better explained by changes in CD4+ T-cell counts.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Inverse correlation of telomerase activity/proliferation of CD4+ T lymphocytes and disease progression in simian immunodeficiency virus-infected nonhuman primates
Article Abstract:
An increase in telomerase activity and CD4+ T cell proliferation is associated with a delay in HIV disease progression, whereas a decrease in both is associated with rapid disease progression. This was the conclusion of a study of SIV infection in primates.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Limitations in characterization of heterosexual HIV transmission risk: commentary on the models of Downs and De Vincenzi
- Abstracts: Integration of behavioral and relaxation approaches into the treatment of chronic pain and insomnia. Cognitive behavioral therapy vs. zopiclone for treatment of chronic primary insomnia in older adults: A randomized controlled trial
- Abstracts: Association of tuberculosis infection with increased time in or admission to the New York City jail system. HIV-Related Tuberculosis in a Transgender Network--Baltimore, Maryland, and New York City Area, 1998-2000
- Abstracts: Mutations in mitochondrial transfer ribonucleic acid genes in preeclampsia. Identification of monozygotic twins that are concordant for preeclampsia
- Abstracts: DNA of human papillomavirus type 16 in dysplastic and malignant lesions of the conjunctiva and cornea. Cancer -- nature, nurture, or both