Racial group, socioeconomic status, and the development of persistent proteinuria in systemic lupus erythematosus

Article Abstract:

Socioeconomic factors do not explain why lupus patients of Afro-Caribbean or Asian origin have more severe disease than whites. This was the conclusion of a study of 189 lupus patients, 22 of whom were Afro-Caribbean and 6 of whom were Asian.

Research, Health, Social status, Health and race, Ethnic groups

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Distribution of cases of systemic lupus erythematosus at time of first symptom in an urban area

Article Abstract:

There does not seem to be a statistically significant explanation for a cluster of patients with systemic lupus erythematosus (SLE) observed in an urban area of the United Kingdom. Researchers statistically analyzed the distribution of 188 reported cases of SLE observed during an 11 year period in the greater Nottingham area. There was a cluster of 12 SLE cases found in the area around Nottingham City. None of the patients had any contact with the others nor were they related. When analyzed independently, no community had a disproportionate number of SLE cases as compared to the general population. However, the combination of the cases from two adjacent communities showed a significantly high proportion of SLE cases compared to the general population. Further statistical analyses did not support the clustering of these SLE patients.

Nottingham, England

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Post-traumatic leg ulcer

Article Abstract:

It may be advisable to consider underlying system-wide diseases in patients with gangrene. Researchers presented the medical history of a patient with a dog bite on the leg that grew into a 5 centimeter ulcer identified as gangrene. Results from blood and bone marrow tests identified three of 11 factors for systemic lupus erythematosus (SLE) including elevated levels of C reactive protein, antinuclear antibodies and rheumatoid factor. The lupus anticoagulant test was negative. However, treatment with methotrexate, methylprednisolone, and prednisolone resulted in ulcer healing and the return of blood test results to normal levels. There was no further indication of SLE complications six months after treatment and the wound was completely healed.

Case studies, Complications and side effects, Risk factors, Ulcers, Leg, Transplantation of organs, tissues, etc., Organ transplantation, Tissue transplantation, Transplantation, Leg ulcer, Gangrene

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