Reconciling the epidemiology, physiology, and molecular biology of colon cancer
Article Abstract:
Although physicians do not know the exact causes of colon cancer, there is some agreement between theories from physiology, epidemiology and molecular biology. One theory suggests that a lack of calcium could change protein function which mimics a loss of the genetic material affecting one aspect of cell function. An excess of dietary fat, a source of diacylglycerol (DAG), may signal cells to reproduce in excess in response to excess amounts of DAG. Cooked proteins can form arylamines, precursors of chemicals present in people at increased risk of colorectal cancer. Cooking methods affect possible risk for colon cancer. High temperature cooking produces cancer causing substances and promoters. Cooking in fat occurs at a higher temperature than other methods. These theories combine the theories on the physiological basis of colon cancer with epidemiological studies as well as theories from molecular biology.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
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Effect of a decision aid on knowledge and treatment decision making for breast cancer surgery
Article Abstract:
A randomized trail on a group of breast cancer patients is done to evaluate the impact of a decision aid regarding the different surgical treatment options on patient decision making. The results revealed that the decision board improves communication and enables patients to make a choice regarding treatment and the surgeons should consider this instrument while communicating the different surgical options to patients with breast cancer.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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Antibiotic use in relation to the risk of breast cancer
Article Abstract:
The relationship between the use of antibiotics and the risk of breast cancer was studied. The study reveals that the use of antibiotics is associated with increased risk of incident and fatal breast cancer.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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