Recovery of CD4(super +) T cells in HIV patients with a stable virologic response to antiretroviral therapy is associated with polymorphisms of interlukin-6 and central major histocompatibility complex genes
Article Abstract:
A study was conducted to investigate whether polymorphisms in genes associated with HIV disease progression and/or immune activation affect CD4(super +) T-cell recovery in HIV patients who began combination antiretroviral therapy (ART) with advanced immunodeficiency and achieved stable control of plasma viremia. It is suggested that immune activation and/or CD4(super +) T-cell apoptosis in HIV patients on effective ART is influenced by genetic factors.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Is moderate HIV viremia associated with a higher risk of clinical progression in HIV-infected people treated with highly active antiretroviral therapy?
Article Abstract:
A cohort study is conducted to survey the risk of clinical progression (CP) in HIV-infected people, undergoing highly active antiretroviral therapy (HAART) and possessing a stably suppressed viremia. The analysis shows that a lower level of CP exists with a lower level of HIV viremia, as virologic failure to antiretroviral drugs is very common.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
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