Recurrent allergic vulvovaginitis: treatment with candida albicans allergen immunotherapy

Article Abstract:

Vaginal infections with Candida albicans (yeast) cause itching, discharge and painful intercourse. In some women, chronic Candida infections do not respond to conventional agents used to control the infection. Although diabetes mellitus, birth control use and some recent antibiotic therapies can predispose the vagina to Candida overgrowth, other factors are thought to play a role in chronic infections. An allergic response to Candida produced by a defect in the immune system is one of many possible explanations of chronic Candida infections. Immunotherapy is a technique used to boost the patient's own immune system by administering increasingly higher doses of the offending organism to build up immunity to the organism. To see if immunotherapy resolves Candida infections in women who are hypersensitive to the fungus, 18 women were studied. An initial skin test was performed to determine whether women were sensitive to the Candida organism. A skin test was considered positive if a red mark was produced after a skin prick with the Candida antigen. Of the 18 skin tests, 15 had immediate positive skin tests and three had a late reaction. Immunotherapy injections offered symptomatic improvement in 16 of the patients, reducing the number of Candida infection from 17.2 to 4.3 infections per year. This was a 79 percent overall improvement. It is concluded that a subgroup of women allergic to Candida albicans in the vagina can benefit from standard immunotherapy. (Consumer Summary produced by Reliance Medical Information, Inc.)

Usage, Evaluation, Physiological aspects, Candida albicans, Immunotherapy, Skin tests, Allergy desensitization, Allergens

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Signs of chronic stress in women with recurrent candida vulvovaginitis

Article Abstract:

A study was conducted to determine whether there is an association between recurrent vulvovaginal candida and chronic stress. The higher incidence of vulvovaginal infections in these women compared with control subjects might reflect impaired immunity that might be due to chronic stress.

United States, Health aspects, Diagnosis, Depression, Mental, Depression (Mood disorder)

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Severe vulvovaginitis associated with intravaginal mystatin therapy

Article Abstract:

The case of a woman who developed a severe allergic reaction to the antifungal drug nystatin is reported. She had been using vaginal tablets of nystatin to treat a vaginal yeast infection.

Case studies, Complications and side effects, Drug allergy, Drug hypersensitivity, Nystatin

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