Cognitive function in postmenopausal women treated with raloxifene

Article Abstract:

The drug raloxifene does not appear to affect intellectual ability either positively or negatively, according to a study of 7,478 postmenopausal women with osteoporosis. This drug is used to treat osteoporosis, and because it resembles estrogen, researchers believed it might prevent a decline in intellectual ability in the same way that estrogen does.

Cognition, Osteoporosis

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Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women

Article Abstract:

The Raloxifene Use for The Heart (RUTH) trial was conducted to assess the risks and benefits of treatment with raloxifene in women with or at increased risk for coronary heart disease (CHD) with the aims of determining effects on coronary outcomes and invasive breast cancer. Results show raloxifene did not significantly affect the risk of CHD, but the benefits of raloxifene in reducing the risk of invasive breast cancer need to be weighed against the increased risks of venous thromboembolism and fatal stroke.

Health aspects, Cardiovascular diseases, Breast cancer, Postmenopausal women

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Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene: Results From a 3-Year Randomized Clinical Trial

Article Abstract:

Raloxifene appears to be effective in reducing bone fractures in postmenopausal women who have osteoarthritis. Raloxifene blocks the estrogen receptor. Researchers randomly assigned 6,828 postmenopausal women with osteoarthritis to take 60 or 120 milligrams of raloxifene or a placebo every day. Over the next three years, 5% of those who took 120 mg per day had a vertebral fracture compared to 7% of those taking 60 mg and 10% of those taking a placebo. The rate of other bone fractures was similar in all three groups. Women who took raloxifene had three times the risk of abnormal blood clotting compared to the placebo group.

Statistical Data Included, Prevention, Fractures (Injuries), Fractures, Vertebrae, Spinal fractures

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