Renal-cell carcinoma
Article Abstract:
Kidney cancer accounts for only 2% of all cancers but it can be difficult to treat. Small tumors produce no symptoms, so the disease is often diagnosed when it has advanced. Signs and symptoms include abdominal pain, blood in the urine and a mass in the back or abdomen. CT and ultrasound scans can detect 94% and 79% of cases, respectively. Biopsy can confirm the diagnosis. Surgery is the treatment of choice, since the tumor does not respond to most chemotherapy drugs or radiation. Five-year survival rates range from 65% to 85% in those with local cancer, 15% to 35% in those with lymph node involvement and 10% or less in those with distant metastases.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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Testicular germ-cell cancer
Article Abstract:
The cure rate for testicular germ-cell cancer is very high if the tumor is detected early. Germ-cell tumors are tumors that arise in the sex glands but may also appear outside these glands. Their cause is not known but they seem to have a hereditary component. They first present as a mass in a testicle which may be accompanied by testicular pain, swelling and hardness. An ultrasound scan can confirm the diagnosis. The testicle is surgically removed and followed by radiation and chemotherapy if necessary. About 90% of patients with germ-cell cancer can be cured.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
Article Abstract:
The result of a randomized phase 3 trial of sunitinib as compared with interferon alfa, which is first-line treatment of metastatic renal-cell carcinoma, is reported. The findings reveal that the progression-free survival is longer and response rates are higher in patients with metastatic renal-cell cancer who received sunitinib than in those receiving interferon alfa.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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