Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

Article Abstract:

The study shows that the administration of a glycogen synthase kinase-3 (GSK-3) inhibitor to recipient mice transplanted with mouse or human hematopoietic stem cell (HSCs) can lead to hematopoietic repopulation. The results prove that the GSK-3 is a very essential vivo modulator of HSC activity and can also result in the enhancement of the repopulating capacity of the transplanted HSCs by the means of its inhibitors.

Canada, Patient outcomes, Hematopoietic stem cells, Hematopoietic stem cell transplantation

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Multifunctional [T.sub.H]1 cells define a correlate of vaccine mediated protection against Leishmania major

Article Abstract:

The importance of the probability that T-Cells might help in developing vaccines that may be protective against HIV, tuberculosis infection and other pathogen related diseases is observed.

United States, Drug therapy, CD4 lymphocytes, Leishmaniasis

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