Modulation of vascular tone by nitric oxide and endothelin 1 in myometrial resistance arteries from pregnant women at term
Article Abstract:
Nitric oxide and endothelin 1 are involved in the changes in resistance to blood flow that occur during pregnancy. This was the conclusion of a study on myometrial biopsy tissue.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
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Preeclampsia: evidence for impaired shear stress-mediated nitric oxide release in uterine circulation
Article Abstract:
Nitric oxide may fail to dilate arteries during preeclampsia, and this could explain the decreased placental blood flow that occurs. Preeclampsia is a serious complication of pregnancy.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
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Role of nitric oxide in the regulation of vascular tone in pressurized and perfused resistance myometrial arteries from term pregnant women
Article Abstract:
The shear stress created by the force of blood flow in the uterine arteries and subsequent effects on nitric oxide levels may play an important role in the regulation of fetal blood flow. Flow responses in uterine arteries taken by biopsy at cesarean section from 14 women were evaluated with a pressure ateriograph. Untreated arteries dilated in response to increased flow, but this effect was reversed in arteries treated with a nitric oxide synthesis inhibitor. In arteries constricted in response to norepinephrine, constriction was enhanced in the presence of the inhibitor.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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