Should intracerebroventricular nerve growth factor be used to treat Alzheimer's disease?
Article Abstract:
The use of intracerebroventricular administration of nerve growth factor (NGF) for the treatment of Alzheimer's disease (AD) remains controversial. The symptomatology of AD is explained by the loss of cholinergic transmission due to cell death. Neuronal death on the meantime, is due to inadequate growth factor and thus, theoretically, NGF infusion was proposed because it restores the functions of cholinergic neurons. The use of the trophic hormone as therapy for AD however, deserves further studies and complications inherent to the infusion such as infection limit its therapeutic use.
Publication Name: Perspectives in Biology and Medicine
Subject: Health
ISSN: 0031-5982
Year: 1992
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Changing patterns of communicable disease: who is turning the kaleidoscope?
Article Abstract:
The fight against communicable diseases requires the full participation of all individuals, from medical scientists to ecologists and veterinarians, whose task is to decide which diseases should be given priority in terms of research and resources. To perform this role effectively, they have to consider a wide array of factors that influence patterns of communicable disease such as human demographics and behavior, technology and industry, economic development, international travel and enforcement of public health measures.
Publication Name: Perspectives in Biology and Medicine
Subject: Health
ISSN: 0031-5982
Year: 1995
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Disquisition on Human Adjuvant Disease
Article Abstract:
Human Adjuvant Disease (HAD) which is a part of the autoimmune conditions in human beings is caused by the contact of the human body with microorganism of foreign origin. The HAD defined by genes is associated with the rejection of the non-self as a technique of protecting the body against alien organisms entering the body.
Publication Name: Perspectives in Biology and Medicine
Subject: Health
ISSN: 0031-5982
Year: 1995
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