Telomerase and the aging cell: implications for human health
Article Abstract:
Two 1998 studies show that scientists may be able to extend life and possibly reduce the frequency of age-related diseases. Formerly, research showed that most cells continue to divide up to a point but ultimately lose this ability and show signs of aging. Cell aging was linked to the shortening of the ends of chromosomes after each division. These ends are called telomeres. The 1998 studies showed that cell aging could be reversed by introducing an enzyme called telomerase into the cells. The enzyme lengthens the telomeres, causing the cell to revert to a younger age.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Telomeres, cancer, and aging: altering the human life span
Article Abstract:
Any cost projections for treating elderly people in the future need to consider the fact that scientists may be able to change the aging process. While the average lifespan has increased in the past 200 years, the maximum age remains at about 120 years. However, animal research has shown that maximum lifespan can be extended by restricting dietary calories. Cellular aging is believed to result from genetic changes that prevent the cell from neutralizing damaging free radicals. Many cancer cells are immortal and can continue dividing indefinitely without aging.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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The Ethics of Embryonic Stem Cells--Now and Forever, Cells Without End
Article Abstract:
The ethical problems of using embryonic stem cells for therapeutic purposes are discussed. Embryonic stem cells are cells taken from an early-stage human embryo. These cells have the potential to create any tissue in the body. For this reason, they could be used to create organs for transplantation.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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