Testosterone Replacement and Resistance Exercise in HIV-Infected Men With Weight Loss and Low Testosterone Levels
Article Abstract:
Testosterone or exercise are beneficial in increasing muscle strength in HIV-infected men. Researchers randomly assigned 61 HIV-infected men to one of four groups: placebo and no exercise, placebo and exercise, testosterone and no exercise, or testosterone and exercise. The treatments lasted for 16 weeks. Men treated with testosterone alone, exercise alone, or both experienced significant increases in muscle strength compared to the placebo group. Lean body mass also increased in men treated with testosterone alone testosterone plus exercise. Testosterone and exercise together did not produce greater gains than either treatment alone.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men
Article Abstract:
Testosterone appears to increase muscle mass and strength in healthy men. Forty men were randomly allocated to one of four treatment groups: intramuscular injections of 600 milligrams of testosterone each week or placebo, testosterone plus exercise or placebo plus exercise. The study lasted for 10 weeks. The men who received testosterone had greater increases in muscle size and strength than those who received placebo. Those who received testosterone and also exercised had even greater increases in muscle mass and strength. None of the men experienced hostility or excessive anger during the study.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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Resistance Exercise and Supraphysiologic Androgen Therapy in Eugonadal Men With HIV-Related Weight Loss: A Randomized Controlled Trial
Article Abstract:
The anabolic steroid oxandrolone appears to be effective in increasing body mass in HIV patients.Researchers randomly assigned 22 male HIV patients to do resistance exercise training plus take oxandrolone or a placebo for eight weeks. Both groups increased body mass, weight and strength, but the increases were greater in the men who took oxandrolone.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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