The Swedish prostate cancer paradox

Article Abstract:

A 1997 report from Sweden reveals that aggressive treatment of localized prostate cancer may not be necessary and that watchful waiting may be an equally effective option. However, Sweden's mortality rate from prostate cancer ranks fourth in the world compared to the US rate, which ranks 13th. In the US, the incidence of prostate cancer doubled in the 1990s, mostly due to increased screening. This screening has lowered mortality rates, especially in men younger than 75. Treatment in the US tends to be more aggressive, but even US doctors agree that watchful waiting may be beneficial in some groups of men.

Swedes

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Management of Prostate Cancer After Prostatectomy: Treating the Patient, Not the PSA

Article Abstract:

Doctors should take many other factors besides the prostate-specific antigen (PSA) level into account when assessing men treated for prostate cancer. Elevated PSA levels indicate the presence of prostate cancer and possible its recurrence after treatment. However, a 1999 study of men treated with prostatectomy found that 63% of those with rising PSA levels after treatment were still disease-free five years later. Other important factors include the Gleason score of the tumor before it was removed. Inappropriate concern over rising PSA levels can lead to unnecessary treatments.

Development and progression, Prostate-specific antigen, Prostate specific antigen

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Survival after radical prostatectomy

Article Abstract:

Survival after prostate removal for prostate cancer depends to a large extent on the characteristics of the tumor. Researchers analyzed the records of 3,626 patients with prostate cancer who had been treated with a prostatectomy. The patients resided in nine regions throughout the US. There were no significant differences in survival between regions. Survival rates were lower in men with advanced, poorly differentiated cancer that had spread beyond the prostate. Overall survival was also linked to age and race.

Prostatectomy

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