A 29-Year-Old Man With Multiple Sclerosis. (Clinical Crossroads)
Article Abstract:
Multiple sclerosis (MS) is an autoimmune disease caused by inflammation in the optic nerves, brain, and spinal cord. This causes vision disorders, numbness and weakness, which are the initial symptoms in most patients. In 90% of cases, symptoms begin before the age of 50. Environmental factors are thought to trigger the disease although there is also a clear genetic component. Many patients have relapsing-remitting MS (RR-MS), which is characterized by relapses. This usually turns into progressive MS. About 10% of patients have mild disease with little disease progression and minimal disability. Interferon beta-1b, interferon beta-1a, and glatiramer acetate are the most effective treatments.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Cardiac Actions of Erythromycin: Influence of Female Sex
Article Abstract:
Women may be more susceptible to the side effects of erythromycin than men. Of 346 cases of heart arrhythmia caused by erythromycin, 58% were women. Of the 49 life-threatening arrhythmias and deaths, 67% were women. This was true even though prescriptions for erythromycin were equally distributed between the sexes. Female rabbit hearts were more likely to respond negatively to the antibiotic than male rabbit hearts.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
User Contributions:
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