Treatments for wasting in patients with the acquired immunodeficiency syndrome

Article Abstract:

There are many treatments for the wasting syndrome that occurs in many AIDS patients. Wasting syndrome is diagnosed if the patient has lost more than 10% of body weight and also has diarrhea, weakness or fever. Nutritional supplements and appetite stimulants may be effective as can testosterone and other anabolic steroids. Growth hormone may be beneficial in high doses but the safety of long-term use is unknown. Exercise may be beneficial but the effects of regular exercise in people with wasting syndrome is unknown. The development of more effective AIDS drugs may reduce the risk of wasting syndrome.

Care and treatment, Wasting syndrome, AIDS (Disease)

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Metformin in the Treatment of HIV Lipodystrophy Syndrome: A Randomized Controlled Trial

Article Abstract:

The drug metformin may be effective in treating lipodystrophy syndrome in HIV patients. Lipodystrophy syndrome causes a redistribution of fat, including an increase in fat on the trunk and abdomen and a loss of fat on the face and extremities. Another sign of lipodystrophy is insulin resistance, which is considered a precursor of diabetes. In a study of 26 HIV patients with lipodystrophy syndrome, metformin improved insulin metabolism and reduced abdominal fat.

Evaluation, Drug therapy, Metformin, Lipid metabolism disorders, Lipidosis

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Growth hormone-releasing hormone in HIV-infected men with lipodystrophy

Article Abstract:

The human immunodeficiency virus (HIV) lipodystrophy syndrome is rampant in patients receiving antiretroviral therapy and tests were conducted to study the effects of growth hormone-releasing hormone (GHRH) in treatment of this syndrome. GHRH was tolerated while increasing levels of IGF-1 in HIV -infected men with lipodystrophy.

United States, Science & research, Research, Usage, Influence, Somatotropin releasing hormone, Somatotropin-releasing hormone, Highly active antiretroviral therapy, Lipodystrophy

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