Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
Article Abstract:
Mice who lack pro-opiomelanocortin peptides are obese and have defective adrenal function and altered pigmentation. An alpha-melanocyte-stimulating hormone agonist caused the mice to lose more than 40% of their body weight.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
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Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor
Article Abstract:
The Y2 receptor for neuropeptide Y plays an inhibitory role in the regulation of food intake and body weight. Rats witih an inactive receptor ate more food, gained weight and had increased fat deposits.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
User Contributions:
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