Yersinia pseudotuberculosis and arthritis

Article Abstract:

Reactive arthritis is an inflammation of the joints associated with infection by a microorganism. In Great Britain, reactive arthritis may result from infection with the bacteria Yersinia enterocolitica, but is rarely associated with infection by Yersinia pseudotuberculosis. The records of patients in Oxford who had yersinia infections in 1986 and 1987 were reviewed to determine the relation between specific types of yersinia infections and the occurrence of reactive arthritis. In the presence of foreign invading particles such as bacteria, B cells of the immune system produce specialized proteins called antibodies, which bind and inactivate the foreign particle. Nine patients were shown to have antibodies to Yersinia pseudotuberculosis, and antibodies in two of these patients were also reactive against salmonella-type bacteria. Among the remaining seven patients, three had severe arthritis or inflammatory joint disease and two had symptoms of sacroiliitis, or inflammation of the sacroiliac joint, located in the lower hip. Review of the literature indicates that reactive arthritis may be a complication of both Y. enterocolitica and Y. pseudotuberculosis infections. (Consumer Summary produced by Reliance Medical Information, Inc.)

Joint diseases, Yersinia infections

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Staphylococcus aureus triggered reactive arthritis

Article Abstract:

Staphylococcus aureus infection can trigger a reactive, transient arthritis, although it is not an infective agent commonly implicated in this reaction. Reactive arthritis is an inflammation of a joint in response to an infection elsewhere in the body. Two cases are reported. A woman undergoing kidney dialysis because of kidney failure resulting from cancer first had an episode of Staph aureus infection in her elbow joint. The infection was cured, but one week later she developed inflammation in her knee. Cultures of joint fluid samples were negative. She was treated and recovered. A few months later she had another Staph aureus infection from a catheter, which again resulted in knee joint inflammation that was culture negative. Again, she was treated and recovered. The second case was a healthy woman with a Staph aureus infection in the muscle of her thigh and her arm. Blood culture was negative. Six days later both knees became inflamed. Joint fluid cultures were negative. She was treated and recovered.

Staphylococcal infections

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Association between human parvovirus B19 infection and arthritis

Article Abstract:

Parvovirus B19 may be an infectious trigger of arthritis. Typically, parvovirus B19 causes erythema infectiosum, a mild childhood disease. Blood samples were analyzed for parvovirus B19 DNA and anti-B19 IgG antibodies and IgM antibodies in 54 adult patients with various types of arthritic diseases, including 15 patients with arthritis suspected to be of viral origin. The presence of IgM antibodies indicates recent infection whereas IgG antibodies will be found over the long term. Overall, 63% of patients had anti-B19 IgG antibodies. Among patients whose arthritis was suspected to be of viral origin, 93% had anti-19 IgG antibodies. Anti-B19 IgM antibodies were found in 13 patients (25%) overall, of whom 8 had arthritis suspected to be of viral origin. No patient with rheumatoid arthritis or arthritis resulting from mechanical stress or injury had anti-B19 IgM antibodies. B19 DNA was found in 8 patients, of whom 7 had arthritis of viral origin.

Parvoviruses

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