Schizophrenia, the dopamine hypothesis and alpha(sub)2-adrenoceptor antagonists
Article Abstract:
This article discusses the hypothesis on the role of dopamine in the treatment of schizophrenia. Recent findings indicate that the hypothesis is not unequivocal and antipsychotic drugs possessing D2-receptor and alpha(sub)2-adrenoceptor blocking activity provide better clinical efficacy.
Publication Name: Trends in Pharmacological Sciences
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0165-6147
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Endocannabinoids and multiple sclerosis: a blessing from the 'inner bliss'?
Article Abstract:
This article discusses the role of endocannabinoids in the treatment of neurological disorders. Results indicate that the endogenous and exogenous delta(sup)9 tetrahydrocannabinol compounds reduce spasticity and tremors associated with multiple sclerosis.
Publication Name: Trends in Pharmacological Sciences
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0165-6147
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Anandamide and the question of its functional role for activation of capsaicin receptors
Article Abstract:
This article discusses the activation mechanism of vanilloid VR1 capsaicin receptors on afferent neurons by anandamide. Results suggest that anandamide released from the peripheral tissues may be enough to activate a set of receptors.
Publication Name: Trends in Pharmacological Sciences
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0165-6147
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Pharmacological prospects for alpha2-adrenoceptor antagonist therapy. Application of in situ microdialysis to measure metabolic and vascular responses in adipose tissue
- Abstracts: RAMPs: accessory proteins for seven transmembrane domain receptors. Urotensin II: fish neuropeptide catches orphan receptor
- Abstracts: D-Tagatose, a novel humectant and sweetner for toothpastes. The synergistic antioxidative effect of ascorbyl 2-phosphate and alpha-tocopheryl acetate
- Abstracts: US: SWISS CONTRACTS FOR SYMIX. Switzerland: Ciba licences Janssen light stabilisers. GERMANY/US: AGREVO, 3DP RESEARCH ALLIANCE
- Abstracts: GERMANY: REORGANISATION AT WELLA. Germany: Wella forecast for markets, profits. GERMANY: COSMETIC, DETERGENT FIRMS CONFIDENT