Catalytic enantioselective conjugate addition with Grignard reagents
Article Abstract:
The advances in catalytic asymmetric conjugate addition of Grignard reagents are presented and the scope of the technique is described. The mechanistic study of the catalytic process and the application of the catalytic system to the enantioselective [S.sub.N] 2' substitution reactions of allylic bromides with Grignard reagents are presented.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
Applications of planar-chiral heterocycles as ligands in asymmetric catalysis
Article Abstract:
A new family of ligands for asymmetric transition metal-catalyzed reactions are designed and synthesized. The planar-chiral heterocycles have furnished enantioselectivity in a variety of processes, which includes isomerizations of allylic alcohols, O-H insertions and 1,3-dipolar cycloadditions.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Asymmetric catalysis with "planar-chiral" derivatives of 4-(dimethylamino)pyridine
Article Abstract:
'Planar-chiral' derivatives of 4-(dimethylamino)pyridine (DMAP), a highly versatile nucleophilic catalyst, is developed that are effective in various processes, including the Staudinger synthesis of beta-lactams, the acylation of silyl ketene acetals, and the kinetic resolution of amines.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Martian field test: Drilling in Greenland to prepare for Mars. Splash of cold water
- Abstracts: California's largest setback levee completed with unique funding and reused material. Sensors designed to protect famous covered bridges
- Abstracts: Alternative energy: wastewater facility benefits from wind, solar power. Urban wetlands restoration begins in New York, New Jersey
- Abstracts: Viral nano electronics. Half-brained schemes. Math without words: Numerical reasoning seems independent of language
- Abstracts: Advanced composite panels for seismic and vibration mitigation of existing structures. Relaxation of proton conductivity and stress in proton exchange membranes under strain