Characterization of dietary exposure to planar halogenated hydrocarbons, dioxin equivalents, and biomagnification

Article Abstract:

Minks are among the most sensitive mammalian species to the reproductive toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. This was confirmed by a study of the chemical characterization of the diets and the adult mink livers. An additive model of toxicity was compared with the results of the H4IIE bioassay on samples of their diets and livers. Dioxin-like potency of the planar halogenated hydrocarbon (PHH) mixtures mostly followed an additive model of toxicity. Dietary and liver tissue-based threshold concentrations for reproductive toxicity in mink were consistent regardless of whether PHHs were quantified as additive toxicity or H4IIE bioassay.

Food and nutrition, Contamination, Animals, Minks, Animal food, Reproductive toxicology

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Response to comment on "butyltin contamination in marine mammals from North Pacific and Asian coastal waters."

Article Abstract:

The use of marine mammals for environmental research is justified by the wealth of new information about the effects of toxic chemical pollution on marine life. The research programs necessitate the use of marine mammals to determine fully the extent the damage that toxic contaminants may have brought to marine animals from North Pacific and Asian coastal waters. No endangered species of animals, either dead or alive, are used in the research programs.

Testing Laboratories, Hunting, trapping, game propagation, Hunting and Trapping, Marine Mammals, Environmental Testing Labs, Environmental aspects, Environmental testing, Environmental laboratories

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